Born in Ireland, John Brougham originally pursued a surgical career at the Peter Street Hospital in Dublin. A change in fortune resulted in his decision to move to England and become an actor in 1830. He was associated with London's Tottenham Street Theatre, the Olympic Theatre, and became manager of the London Lyceum in 1840. Brougham produced over 100 works and is remembered for his comedic playwriting and acting.
Born to a family of tradesmen in New York City, Charles Gayler began his career as a teacher before he moved to Ohio and worked as a journalist and editor. While there, he developed an interest in politics that led him to write songs and speeches for Whig Presidential candidate Henry Clay in the 1844 election. In 1846 he married Grace Christian, with whom he had eight children. While one source suggests that his wife was actress and fellow Pfaffian Getty Gay (Rawson 103), Thomas Butler Gunn indicates that Gay was Gayler’s mistress (10.34).
Known best by his pseudonym of Petroleum V. Nasby, David Ross Locke was born in upstate New York near Binghamton to a poor family. According to his biographer, John Harrison, Locke had "little formal education." (5) Instead, Locke built his career off his own hard work and ingenuity, starting from a very young age. When he was 12, Locke became an apprentice at a Cortland newspaper called the Democrat, a position that lasted for seven years.
While there is scant evidence that Mark Twain (Samuel Clemens) ever visited Pfaff's bar (only one source suggests that he did [Rawson 99]), he was connected to the Pfaff's bohemians in a number of ways.