Very little is known about Ada Clifton’s early life before she came to the stage in New York. Ireland places Ada Clifton’s debut on the New York stage in 1855 and labels her as a pupil of Mrs. Maeder (642). We do know that Clifton eventually performed with Laura Keene's company, and alongside Edwin Booth and John Brougham after joining with the company at Burton’s theatre on Broadway (Wingate 213). Clifton did star as Ophelia opposite Edwin Booth in Hamlet and also appeared in the title role of Aladdin beginning July 23, 1860 (Odell Vol.7).
Though much of her early life, including her real name and exact date of birth, remains in shadow, Laura Keene is thought to have come from a well-to-do background. She was widely read and spent time in Turner’s studio during her childhood. After performing with Madame Vestris’ company, Keene journeyed to New York in 1852 at the invitation of James W. Wallack. She became the leading lady of his theater and enjoyed great success.